Dapsone: What It Is and When It’s Used

Dapsone is an oral antibiotic that also works as an anti‑inflammatory drug. It’s most famous for treating leprosy, but doctors also prescribe it for dermatitis herpetiformis, certain types of pneumonia, and as a second‑line option for some skin conditions. Because it can affect blood cells, it’s usually given under close monitoring.

How to Take Dapsone Correctly

Take dapsone exactly as your doctor tells you. The usual adult dose for leprosy is 100 mg once a day, but for skin disorders the dose may be lower, often 50 mg. Swallow the tablet with a full glass of water; you don’t need food, but a snack can help if you feel an upset stomach.

Never double up if you miss a dose. Just skip the missed one and keep to your regular schedule. If you’re on a long‑term plan, expect blood tests every few months – the lab will check your hemoglobin and white‑cell count to catch any problems early.

Side Effects and When to Call Your Doctor

Most people tolerate dapsone well, but common side effects include mild nausea, loss of appetite, and occasional headache. A more serious reaction is hemolytic anemia, especially in people with G6PD deficiency. Signs are sudden fatigue, pale skin, shortness of breath, or dark urine. If any of these appear, call your doctor right away.

Skin reactions can also happen – rash, itching, or a fever may signal a drug allergy. Discontinue the medication and seek medical help if the rash spreads or you develop blisters.

Because dapsone can interfere with other medicines, tell your doctor about every drug you take, including over‑the‑counter pain relievers, vitamins, and herbal supplements. Notable interactions are with antimalarials, certain blood thinners, and drugs that also cause low blood counts.

Pregnant or breastfeeding women should discuss risks with their provider. Dapsone crosses the placenta and can affect the baby’s blood cells, so doctors weigh benefits against potential harm.

In summary, dapsone is a useful tool for specific infections and skin diseases when used correctly. Stick to the prescribed dose, attend regular lab check‑ups, and watch for warning signs. With these steps, you’ll minimize risks and get the most benefit from the medication.